I moved this to the PS3 Online section as it isn't a PS3 hack... to answer though, PS3 runs it from the XMB so you don't do it via Linux or Windows.
The project is currently managed by the Pande Group, within Stanford University's chemistry department, under the supervision of Professor Vijay Pande.
PS3 Firmware v1.6 (released on Thursday, March 22, 2007) first allowed for Folding@home software on the PS3 via Sony's client.
On September 18, 2008 the Folding@home client became Life With PlayStation which added information "channels", the first of which being the Live Channel which offers news headlines and weather through a 3D globe.
More F@H background info is available here: