My assumption will be that you will require the new update because Sony have done this in the past with the PSP so they will definitely do it on one of their biggest releases. But there may be a possibility that it can be patched to work in 3.41 like Yoshihiro did on PSP. Time will tell all.
Yeah Prolog has been out for ages and I already own the original. Well I'm not sure if it will be required to use 3.42 or 3.50 as its due for release in 2 months and they may have already been started making copies.