There are no issues with it. I have a Slim 120 (with a 500 GB drive now) and it runs fine. I have also installed Slim 80 and a Fat 60 without any issues. Just remember, Kmeaw does not have a BD Emulator payload built in, so you will need to add one. If you are using MulitMan, simply download the BDEMU.PKG attached to its thread and install that.